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Can you play Resident Evil 6 completely solo?

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Can you play Resident Evil 6 without any partner of any kind? Not even an AI partner? On all campaigns? Or do we at least have a setting that lets us make our partner not help us at all? Or make it so that they cannot kιll enemies? I really wanna know, because I have managed to make RE5 more survival horror-like by limiting my AI partner's capabilities, and I want to do the same for RE6.