How much money will I spend on gas to go to Florida from Maryland
Well as ichibanarky said, we don't have all the details we need to figure, but this is how you would do it. Find how many miles it is from your starting point to end point (mapquest), then take that and divide it by how many miles you get to the gallon. Then take that and multiply by the average cost of gas. :) This is just an approximated value, it won't be exact.
Depends on how good your car is on mileage, how fast you drive, whether or not you use air conditioning, etc...