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How can I get my computer back to normal?

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Okay, so right now I am using safe mode because every time I click on start computer it wouldn't let me, normally I would type my password and it would say "profile bad, so the only option is to use safe mode..how can I fix it..what happens if I delete everything..I did it once on my laptop where I call the customer service and they helped me start my computer new and fresh..but this is a desktop..what should I do?