This is one of my favs. Josh Harnett and Jennifer Miller in Lucky Number Slevin http://funadvice.com/r/3nirmbhbgd
Forgetting Sarah Marshall - he get's broken up with in the beginning while he's naked...hilarious.
Funny People. (towards the end) Hancock. (end of the movie) Almost Famous. (When penny lane is ignored by the band member whose wife is there and she goes back to her room and over doses) Meet Bill. (Hilarous break up scene when he finds his wife cheating with a local news anchor)
Scott pilgrim vs the world. scott breaks up with knives and her face looks like she got punched! its sad and hilarious at the same time and hes just like well that weird! =D
I adore Almost Famous!