What guitar brands are the best?
Les Paul is a model, not a brand.
When you say BEST, that depends on what you're using it for. If you mean 'most expensive' ...Parker, PRS, Gibson, Taylor, Guild, etc. there's a lot of overpriced gear out there.
Gibsons are too heavy & muddy for my taste.
I've always preferred Fender to Gibson.
Fener and Gibson