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Why my computer doesn't have sound?

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My computer just all of a sudden doesn't have any sound at all!(my speaker is inside the monitor kind). I tried start>control panel>sound and audio devices and everything was just not able to be click on! Also, the little speaker icon was not on the start bar! I recently 'disk cleanup' my computer and installed netscape navigator due to the failure of mozilla firefox. I thought it was the media players that effects the speaker, so I uninstalled real player and window media player then reinstalled again! But the situation stays the same, nothing changed! Can you please help me with my speaker! :<