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The two previous answerers failed to check the category: Pets Animals.
The answer is because each time an animal is born it inherits both the good and bad mutations that exist in its parents. By inbreeding you double the chances of the negative mutations becoming predominant in the offspring. This is what causes species to become extinct -- they get locked into a confined area and start inbreeding until the negative mutations cause them to die off.
That's why zoos bring in animals temporarily from other zoos to breed -- to prevent the blood lines from becoming weak.
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Answer this Question: "Father-daughter and mother-son breeding"
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Father-daughter and mother-son breeding
Father-daughter and mother-son breeding... I would like to know what the big deal is...