Villanueva de Sigena or Villanueva de Sijena is a small village in Los Monegros, in the province of Huesca, autonomous community of Aragon (Spain), near the Alcanadre river. The Monastery of Santa María de Sigena is located close to this town. Villanueva de Sigena is the birthplace of the physician and heterodox theologian, Michael Servetus (1511-1553). Servetus was the discoverer of pulmonary circulation. A museum and interpretation center is maintained by the Michael Servetus Institute at the old house were Servetus was born, after a major restoration in 2002.