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heart muscle cells can begin to die as quickly as 30 minutes after circulation has been halted and the tissues have become ischemic, after 2 hours nearly half of the cells in the affected area will die, after 4 to 6 hours 90% of the cells in the affected area of the heart will be dead.
these dead necrotic cells will eventually become scar tissue which will create a burden for the heart and make it more difficult to circulate blood.
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How quickly does irreversible damage occur after a myocardial
 



How quickly does irreversible damage occur after a myocardial
infarction and how does the necrosis affect the function of the heart?