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I'd check with your vet but suspect that anytime soon would be fine. You really want to catch her before she has her first season as the risks of mammary tumours and other associated cancers is vastly reduced.
As with all surgery, there are risks but I think any vet would agree the health benefits of spaying far outweigh the possible surgical/anaesthetic risks involved.
My border collie, Sam, was spayed around 6 months-ish and she made a very quick recovery. I wouldn't worry too much, you're doing what's best for your dog.
Good luck
Diane
http://www.animalloversweb.com
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When to get my puppy spayed?
just wondering when is the best time to have my female puppy spayed she is currently 5 months old and has nt had a first season yet