How to help my best friend who's in trouble?

My life is filled with my own problems...but im mre concerned about my best friend dev. shes gone emo, anerxic, depressed, hangin with people on drugs, and becoming less reiligous. im loosing her...what do I do?

Ok so the drugs are a problem,
But I think you're confusing anorexia and depression with a not eating and sadness.
Those are actually medical conditions that you cant just 'be'.
There's nothing really wrong with being emo,
I know it might not be ideal for you but its just a style,
But the being less religious thing is entirley decision and you CANNOT hold that against her.
If shes determind to be self destructive, shes going to continue like this and theres not much you can do to help her.
Now you have a choice,
you can either:-
1. Split ways with her. She is, actually, a bad influence and a source of stress to you.
2. Argue with her about it. This could have the same effect as No. 1 in the end, but there is hope that she could turn it around.
3. Ignore it. Remain her friend and put up with the sh*t.
4. Activley try to change her. Do things with her all the time so she's not with destructive people, make her laugh and compliment her to get her self esteem up.

Confront her or go to a counseler with her and the counseler will talk to you to about it.

thz..but she wont go..me and my girlfriend have tried and tried 2 help..but were loosing her everytime we try.

you could tell her parents for her own sake but if that doesnt work, then you need to tell her, give her a bitter scare, tell her the consequences of her reasoning, let her know what's up, scaring people always works the best! :]

nope.didnt work. now her boyfriend broke up with her so shes worse...what now?

Lol..sounds like fun. Ill try, THX